Novel galenic forms of verapamil, their preparation and medicine

Details Novel galenic forms of verapamil, their preparation and medicine Novel galenic forms of verapamil, their preparation and medicine

1986-09-18

1989-08-22

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Capsules

424457, 424458, 424459, 424461, 424493, 424494, 424495, 424497, A61K 958

Patent

active

048594695

ABSTRACT:
The invention relates to a novel galenic form of verapamil which show an excellent bioavailability. The novel galenic form comprises microgranules containing a verapamil addition salt with an acid, associated to at least one wetting agent. The microgranules are coated with a porous membrane constituted of a synthetic polymer associated to an adjuvant.

REFERENCES:
patent: 4411882 (1983-10-01), Franz et al.
patent: 4521401 (1985-06-01), Dunn
patent: 4629624 (1986-12-01), Grouiller et al.
patent: 4656024 (1987-04-01), Laruelle

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