Monoclonal antibodies and method for detecting dioxins and diben

Details Monoclonal antibodies and method for detecting dioxins and diben Monoclonal antibodies and method for detecting dioxins and diben

1986-06-24

1989-01-17

Warden, Robert J.

Chemistry: analytical and immunological testing

Involving production or treatment of antibody

Monoclonal antibody

436815, 4351722, 435948, 530387, 530808, 935103, 935105, 935110, G01N 3353

Patent

active

047988070

ABSTRACT:
Compositions of matter are described which include five monoclonal antibodies that react with dioxins and dibenzofurans, and the five hybridomas that produce these monoclonal antibodies. In addition, a method for the use of these antibodies in a sensitive immunoassay for dioxins and dibenzofurans is given, which permits detection of these pollutants in samples at concentrations in the range of a few parts per billion.

REFERENCES:
patent: 4238472 (1980-12-01), Albro
patent: 4486530 (1984-12-01), David
patent: 4681848 (1987-07-01), Tsukamoto
Kennel-I, Chemical Abstracts 104: 181193z (1986).
Kennel-II, Chemical Abstracts 106: 16761s (1987).
Luster, Anal. Chem. 52, 1497-1500 (1980).
Kennel-I, Toxicology and Applied Pharmacology 82, 256-263 (1986).
Kennel-II, Chemosphere 15, pp. 2007-2010 (1986).

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