Process of preparing 5-amino-5,6,7,8-tetrahydroquinolines and re

Details Process of preparing 5-amino-5,6,7,8-tetrahydroquinolines and re Process of preparing 5-amino-5,6,7,8-tetrahydroquinolines and re

1993-03-19

1994-05-10

Raymond, Richard L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546183, C07D215227, C07D22104

Patent

active

053109147

ABSTRACT:
Novel 5-amino-5,6,7,8-tetrahydroquinolines and related compounds, intermediates and processes for the preparation thereof, and methods for relieving memory dysfunction utilizing compounds or compositions thereof are disclosed.

REFERENCES:
R. Albrecht and E. Schroeder, Archiv Der Pharmazie, vol. 308; 588-594 (1975), entitled "Chemotherapeutic Nitroheterocycles, 17.sup.1) Condensation Products of Nitrated Heterocyclic Aldehydes with Oxocyclopentathiophenes and Oxotetrahydroquinolines."
L. Mosti, et al., Journal of Heterocyclic Chemistry, vol. 22, 1503-1509 (Nov.-Dec., 1985) entitled "Reaction of 2-Dimethylaminomethylene-1,3-diones with Dinucleophiles V; and Synthesis of 5-Acyl-1,2-dihydro-2-oxo-3-pyridinecarbonitriles and 1,2,5,6,7,8-Hexahydro-2,5-dioxo-3-quinolinecarboxamides".
Y. C. Martin, et al., Journal of Medicinal Chemistry, vol. 16, 147-150 (Feb., 1973), entitled "Potential Anti-Parkinson Drugs Designed by Receptor Mapping".
H. Weber, et al., Chemical Abstracts, 106, 196225b (1987), published in the United States and entitled "Oxidative clevage of psuedobases from 2-.alpha.-alkylated 2,3-cycloalkenopyridinium salts".

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