2-Amino-N-[1,2-Diphenyl-1-(thifluoromethyl)ethyl]acetamide deriv

Details 2-Amino-N-[1,2-Diphenyl-1-(thifluoromethyl)ethyl]acetamide deriv 2-Amino-N-[1,2-Diphenyl-1-(thifluoromethyl)ethyl]acetamide deriv

1987-02-06

1989-01-17

Higel, Floyd D.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

26050121, 544168, 546236, 548561, 562561, 564190, 564194, 564196, 564138, C07C10350

Patent

active

047986875

ABSTRACT:
Compounds are provided of the following general structure: ##STR1## wherein R.sub.1, R.sub.2 and R.sub.3 are independently selected from hydrogen or methyl and A is amino, C.sub.1 -C.sub.4 monoalkylamino, C.sub.2 -C.sub.8 dialkylamino, cyclopropylamino, 1-pyrrolidinyl, 1-piperidinyl or 4-morpholinyl. They are useful for providing sedative and antiepileptic activity.

REFERENCES:
patent: 2719862 (1955-10-01), Bruce et al.
patent: 3950335 (1976-04-01), Schromm et al.
patent: 4015011 (1977-03-01), Schromm et al.
patent: 4073941 (1978-02-01), Lindberg et al.
patent: 4267374 (1981-05-01), Metcalf et al.
patent: 4323704 (1982-04-01), Metcalf et al.
patent: 4536507 (1985-08-01), Rokaett et al.
patent: 4639468 (1987-01-01), Roncucci et al.
CA 64,14162f (Zaheer et al) (1966).
CA 73,25044n (Armando et al) (1970).
CA 77,19586g (Patel et al) (1972).
CA 85,5705y (Hori et al) (1976).
CA 96,19744z (Antoniadou-Vyza et al) (1982).

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