Method for the detection of mucopolysaccharide storage diseases

Details Method for the detection of mucopolysaccharide storage diseases Method for the detection of mucopolysaccharide storage diseases

1991-12-09

1994-05-10

Wityshyn, Michael G.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

435805, 436166, 436169, 436811, 436815, 422 56, C12Q 100, G01N 2175, G01N 2100

Patent

active

053106466

ABSTRACT:
A method for screening a patient for mucopolysaccharidoses is provided in which sample urine absorbed onto a porous sheet and dried is extracted with water. 1,9-dimethylmethylene blue dye reagent in buffer is added to the aqueous extract to produce a test solution which is assessed spectrophotometrically for color change indicative of mucopolysaccharidoses. The invention is particularly applicable to rapid and reliable mass screening and diagnosis of newborn infants.

REFERENCES:
J. Muenzer, Adv. Pediatr., 33, 269-302 (1986).
V. Shih, "Toluidine Blue O Spot Test (Berry Spot Test)" and "Alcian Blue Spot Test", Laboratory Techniques for the Detection of Hereditary Metabolic Disorders, Chap. 5, 103-106; 109-118 (CRC Press).
H. Berry, Clin. Biochem., 20, 365-371 (Oct. 1987).
R. Humbel and S. Etringer, Rev. Roum. Biochem., 11, 21-24 (1974).
Bonsnes and Taussky, J. Biol. Chem., 158, 581-591 (1945).
J. Widom and S. Edelstein, Chemistry (W. H. Freeman & Company: San Francisco, Calif.), 220-221 (1981).
K. Huang et al., Clinica Chimica Acta, 151, 141-146 (1985).
E. Berman et al., Clin. Chem., 16, 886-890 (1971).
H. Berry, Clin. Chem., 5, 603-608 (1959).
H. Berry and J. Spinager, J. Lab. & Clin. Med., 55, 136-138 (1960).
T. Bitter and H. Muir, Anal. Biochem., 4, 330-334 (1962).
R. Burlingame et al., Clin. Chem., 27, 124-128 (1981).
N. Carson and D. Neill, Arch. Disease in Childhood, 505-513 (1962).
G. Coppa et al., Helv. paediat. Acta, 42, 419-423 (1987).
N. Di Ferrante, Anal. Biochem., 21, 98-106 (1967).
R. Farndale et al., Connective Tissue Research, 9, 247-248 (1982).
O. Folin and H. Wu, J. Biol. Chem., 38, 81-110 (1919).
E. Gold, Anal. Biochem., 99, 183-188 (1979).
R. Hata and Y. Nagai, Anal. Biochem., 52, 652-656 (1973).
J. Hobbs et al., The Lancet, 709-712 (Oct. 3, 1981).
D. Hsu et al., Anal. Biochem., 46, 156-163 (1972).
K. Huang et al., Clin. Chimica Acta, 151, 147-156 (1985).
M. Jaffe, "Ueber den Niederschlag, welchen Pikrinsaure in normalem Harn erzeugt and uber eine neue Reaction des Kreatinins", 391-400 (1886).
C. Kodama et al., Clin. Chem., 32, 30-34 (1986).
W. Krivit et al., New England J. Med., 311, 1606-1611 (1984).
M. Lammi and M. Tammi, Anal. Biochem., 168, 352-357 (1988).
A. Mestel et al., Surgery, 57, 795-799 (1965).
M. Moore, University of Minnesota Med. Bull., 2-6 (Winter, 1987).
K. Nanto-Salonen et al., Clinica Chimica Acta, 146, 111-118 (1985).
D. Newton et al., Anal. Biochem., 62, 268-273 (1974).
G. Panin et al., Clin. Chem., 32, 2073-2076 (1986).
C. Pennock et al., Acta Paediat. Scand. 62, 481-491 (1973).
L. Rosenfeld, Clin. Chem. Acta, 31, 263-269 (1971).
L. Rosenfeld, Surgery, 70, 378-384 (1971).
L. Rosenfeld et al., "Determination of `Heparinoid` Substances in Urine with a Dye-Binding Technic," 317-321 (1961).
A. Ruggeri et al., Arzneim.-Forsch./Drug Res., 35, 1517-1519 (1985).
J. Sabater et al., Clin. Gen., 4, 260-263 (1973).
P. Sabiston et al., Anal. Biochem., 149, 543-548 (1985).
P. Sampson et al., Anal. Biochem., 151, 304-308 (1985).
C. Scriver, "Screening Newborns for Hereditary Metabolic Disease", 807-821 (1965).
C. Scriver et al., "Population Screening: Report of a Workshop," Prevention of Physical and Mental Congenital Defects, Part B: Epidemiology, Early Detection and Therapy, and Environmental Factors, 89-152 (1965).
N. Seno et al., Anal. Biochem., 37, 197-201 (1970).
J. Spranger, Am. J. Med. Gen., 28, 489-499 (1987).
I. Staprans and J. Felts, J. Clin. Investigation, 76, 1984-1991 (1985).
K. Taylor and G. Jeffree, Histochemical J., 1, 199-204 (1969).
P. Whiteman, Biochem. J., 131, 351-357 (1973).
C. Whitley et al., Birth Defects: Original Article Series, 22, 7-24 (1986).
H. Berry et al., J.A.M.A., 167, 2189-2190 (1958).
J. Rattenbury et al., J. Clin. Pathol, 41, 936-939 (1988).

Affiliated with

Also associated with

Rating

Method for the detection of mucopolysaccharide storage diseases does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method for the detection of mucopolysaccharide storage diseases, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method for the detection of mucopolysaccharide storage diseases will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2412013