High purity beta-carotene

Details High purity beta-carotene High purity beta-carotene

1992-10-27

1994-05-10

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Food or edible as carrier for pharmaceutical

424451, 424464, 424489, 4241951, 585825, A61K 916, A61K 948, A61K 920, A61K 3578

Patent

active

053105540

ABSTRACT:
Compositions of high-purity natural beta-carotene and of the 9-cis isomer of beta-carotene are provided, as are methods for the production of these compositions from plant matter, conveniently algae such as Dunaliella species. Typically, the compositions contain at least about 5% 9-cis beta-carotene and less than or equal to 40% of all-trans-beta-carotene, and in some cases may contain 75% 9-cis beta-carotene or higher. The compositions are suitable for administration to humans or other animals, particularly for oral delivery, in a variety of formulations and dosages as pharmaceutical agents or as dietary supplements.

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Ben-Amotz et al., "Bioavailability of a Natural Isomer Mixture as Compared with Synthetic all-trans-B-Carotene in Rats and Chicks," J. Nutr. 119(7):1013-1019, 1989.
Ben-Amotz, "The Wavelength Dependence of Massive Carotene Synthesis in Dunaliella bardawil (Chlorophyceae)," J. Phycol. 25:175-178, 1989.
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