Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1995-05-17
1997-07-08
Ivy, C. Warren
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
544124, 544360, 546193, 5462764, C07D21330
Patent
active
056462875
ABSTRACT:
The invention provides a method for synthesizing chiral compounds utilizing novel catalysts which are enantioselective electrophiles via kinetic resolution. The method includes treating a racemic mixture with a reagent which is a chiral DMAP derivative, a chloroformate, a trialkylamine and a Lewis acid to preferentially form a product of one of the enantiomer pair of the mixture. The invention also provides a method for resolving racemic mixture via parallel kinetic resolution.
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Chen Xinhai
Vedejs Edwin
Dahlen Garth M.
Ivy C. Warren
Welch Teresa J.
Wisconsin Alumni Research Foundation
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