Control of mastitis and compositions therefor

Details Control of mastitis and compositions therefor Control of mastitis and compositions therefor

1979-04-19

1981-03-24

Phillips, Delbert R.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Recombinant or stably-transformed bacterium encoding one or...

424309, A61K 31255, A61K 3124

Patent

active

042580560

ABSTRACT:
Neutral to mildly acidic externally-applied mastitis control agents comparable to iodophor teat dips in activity can be obtained from the combination of an anionic surfactant (e.g. an aromatic sulfonate or sulfonic acid) and an aminocarboxylic-type chelating agent. A nitroalkanol antibacterial can be included in the composition. The full strength teat dip contains a major amount of water (but less than 98%) and typically includes an emollient, a buffering agent, and a thickener. The anionic surfactant (which is believed to be effective against gram positive mastitis-causing organisms) and the chelating agent appear to cooperate in the pH range above 4 and below 7. The chelating agent is believed to improve the cell wall permeability of the mastitis-causing organisms, even in this pH range.

REFERENCES:
patent: 2474412 (1949-06-01), Bersworth
patent: 2506492 (1950-05-01), Mytt et al.
patent: 2717243 (1955-09-01), Bloch
patent: 2806789 (1957-09-01), Kiser et al.
patent: 2904468 (1959-09-01), Davis et al.
patent: 3141821 (1964-07-01), Compeau

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