Intermediates for 2'-substituted-spiro[benzofuran-2(3H),1'-cyclo

Details Intermediates for 2'-substituted-spiro[benzofuran-2(3H),1'-cyclo Intermediates for 2'-substituted-spiro[benzofuran-2(3H),1'-cyclo

1985-02-28

1986-06-10

Jiles, Henry R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D30794

Patent

active

045944350

ABSTRACT:
2'-substituted-spiro[benzofuran-2(3H),1'-cycloalkanes] and methods of preparing same are described. On the aromatic portion of the benzofuran ring, there may be a substituent or substituents including halogen, amino, lower-alkyl-substituted amino, lower alkyl, lower alkoxy, hydroxy and nitro. The substituents at the 2-position of the cycloalkane ring are --(CH.sub.2).sub.n NR.sup.1 R.sup.2 where n is 0, 1 or 2 and R.sup.1 and R.sup.2 are each independently hydrogen and alkyl or 1-3 carbons. These compounds are useful as antidepressants and analgesics.
Various other compounds which are useful as intermediates for preparing the aforementioned compounds and methods for preparing same are also described.

REFERENCES:
patent: 4263317 (1981-04-01), Martin et al.

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