Time-integrated measurement for determining substances in biolog

Details Time-integrated measurement for determining substances in biolog Time-integrated measurement for determining substances in biolog

1983-05-09

1986-06-10

Marantz, Sidney

Chemistry: analytical and immunological testing

Biospecific ligand binding assay

128632, 128633, 128635, 128637, 128768, 422 68, 436 52, 436514, 604892, G01N 3350

Patent

active

045943265

ABSTRACT:
A method for obtaining a measurement of the time integral of concentrations of substances in a biological fluid, without the necessity to collect samples of that fluid, and a device useful in the practice of that method. The concepts accomplish time-integrated measurement of the freely-diffusable fraction of substances of interest by providing conditions under which the rate of accumulation of such substances by a device placed in intimate contact with the biological fluid is at all times proportional to their concentration.

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