Protein kinase enzyme AUT-PK 500 and a radioimmunoassay for dete

Details Protein kinase enzyme AUT-PK 500 and a radioimmunoassay for dete Protein kinase enzyme AUT-PK 500 and a radioimmunoassay for dete

Filed on

1984-03-19

Date issued

1986-06-10

Examiner

Wiseman, Thomas G.

Patent Class

Chemistry: molecular biology and microbiology

SubClass

Measuring or testing process involving enzymes or...

SubSubClass

Involving antigen-antibody binding, specific binding protein...

Other Related Categories

435 15, 435 29, 435194, 435810, 436519, 436536, 436543, 436544, 436545, 436546, 436804, 436809, 436813, 436815, 424 11, 530387, 530806, C12Q 100, G01N 3354, C12N 912, C07G 700

Type

Patent

Status

active

Patent number

045943192

Description

ABSTRACT:
This invention is directed to AUT-PK 500, a novel autophosphorylating protein kinase, to the purification and characterization of AUT-PK 500 from rat adrenocortical carcinoma, to the use of AUT-PK 500 as a marker for neoplasia cells, and to a radioimmunoassay for detecting AUT-PK 500 in neoplasia cells.

REFERENCES:
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patent: 3985867 (1976-10-01), Redshaw
patent: 4278653 (1981-07-01), Harris et al.
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Rose, N. R. et al, Methods in Immunodiagnosis, vol. 2nd, ed., J. Wiley & Sons (1980), pp. 147-202.
Ganguly, C. L., Dissert. Abstracts Int. B., #DA8326710, vol. 44(8), 2402 (1983).
Fleischer, N. et al, Methods in Enzymology, vol. 74, pp. 310-320 (1981).
Shanker, G. et al, J. Biol. Chem., vol. 255(8), pp. 3503-3507 (1980).
Shanker, G. et al, Proc. Natl. Acad. Sci., USA, vol. 76(1), pp. 66-70 (1979).
Ganguly, C. et al, J. Biol. Chem., vol. 259(9), pp. 5959-5969 (1984).
Kuroda, Y. et al, Bioch. Biophys. Res. Commun., vol. 112(3), pp. 884-890 (1983).
Sharma, R. et al, Cell. Mol. Biol., vol. 26(1), pp. 65-73 (1980).
Moore, R. E. et al, Cell. Mol. Biol., vol. 25(6), pp. 435-443 (1979).
Yalow and Berson, "General Principles of Radioimmunoassay," Veterans Administration Hosp., Bronx, NY, pp. 7-41.
Green and Gruverman, "Radioactive Drugs", vol. 19, pp. 631-632.

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