Amino-1,2,4-oxadiazolyl-3-acetyl cephalosporins

Details Amino-1,2,4-oxadiazolyl-3-acetyl cephalosporins Amino-1,2,4-oxadiazolyl-3-acetyl cephalosporins

1974-03-13

1976-06-01

Rizzo, Nicholas S.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424246, 2602391, 424271, C07D49944, C07D50120

Patent

active

039608492

ABSTRACT:
Amino-1,2,4-oxadiazolyl-3-acetyl penicillins and cephalosporins of the general formula ##SPC1##
Wherein A is either ##SPC2##
R.sub.1 and R.sub.2 are independently selected from hydrogen and lower alkyl or R.sub.1 and R.sub.2 together with the nitrogen atom to which they are attached form a heterocyclic ring; R.sub.3 is hydrogen, lower alkyl, phenyl, hydroxyphenyl, thienyl, furyl, or pyridyl; R.sub.4 is hydrogen, lower alkyl, phenyl-lower alkyl, benzhydryl, a salt forming ion, trimethylsilyl, or ##EQU1## R.sub.5 is lower alkyl, phenyl or phenyl-lower alkyl; X is hydrogen, lower alkoxy, lower alkanoyloxy, lower alkylmercapto, the radical of a nitrogen base; or certain heterocyclic thio moieties; are disclosed. They are useful as antibacterial agents.

REFERENCES:
patent: 3516997 (1970-06-01), Takano et al.
patent: 3743644 (1973-07-01), Essery et al.
patent: 3821207 (1974-06-01), Chow et al.

Affiliated with

Also associated with

Rating

Amino-1,2,4-oxadiazolyl-3-acetyl cephalosporins does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Amino-1,2,4-oxadiazolyl-3-acetyl cephalosporins, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Amino-1,2,4-oxadiazolyl-3-acetyl cephalosporins will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2402488