Method and apparatus for quantitative surface inhibition test

Details Method and apparatus for quantitative surface inhibition test Method and apparatus for quantitative surface inhibition test

1974-04-01

1976-06-01

Wolk, Morris O.

Chemistry: physical processes

Physical processes

Crystallization

23253R, 23253TP, 23259, 1951035R, 195127, 424 12, G01N 3316

Patent

active

039604888

ABSTRACT:
A metallized slide has adsorbed thereon a first monomolecular layer of particular first immunologically reactive biological particles and is covered with a suitable moisture holding medium. A test solution is then applied along a first edge of the slide, a solution containing second immunologically reactive biological particles specific to the first particles is applied along an edge perpendicular to the first edge, or midway along the slide, and the biological particles in the two solutions diffuse toward each other. The slope or distance from the first edge of a precipitation line formed on the metallized slide at the intersection of the diffused first and second biological particles is related to the concentration of the first particles in the test solution.

REFERENCES:
patent: 3645687 (1972-02-01), Nerenberg
patent: 3674438 (1972-07-01), Shen
patent: 3692486 (1972-09-01), Glenn
patent: 3692491 (1972-09-01), Trentelman
patent: 3709661 (1973-01-01), Hubscher
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patent: 3736100 (1973-05-01), Rains
patent: 3770380 (1973-11-01), Smith
patent: 3843450 (1974-10-01), Saxholm
patent: 3853467 (1974-12-01), Giaever
E. A. Kabat, "Structural Concepts in Immunology," 45, Holt, Rinehart and Winston, New York, 1968.
S. D. Elek, Brit., J. Exptl. Pathol., 30, 484 (1949).

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