N-acyl derivatives of aminoalcohols with polycarboxylic acids ab

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...

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564197, A61K 31155

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active

056188420

ABSTRACT:
N-acyl derivatives of aminoalcohols with bicarboxylic or tricarboxylic acids able to modulate the degranulation process consequent to the mast cells activation in inflammatory processes caused by supramaximal stimuli of neurogenic and immunogenic origin.

REFERENCES:
patent: 4452800 (1984-06-01), Sherlock
patent: 4540626 (1985-09-01), Haas et al.
patent: 4880834 (1989-11-01), Arch
patent: 5312986 (1994-05-01), Simon et al.
Journal Of Neuropathology And Experimental Neurology, vol. 44, No. 2, Mar. 1985, pp. 196-203 (Brosman et al).
Journal Of The Neurological Sciences, 105 (1991), pp. 135-142 (Bo et al).
Medical Hypotheses, 1992, 37, pp. 40-43, (Barker et al).
Neuroscience, vol. 57, No. 3, (1993), pp. 861-871 (Theoharides et al).
The Lancet, Feb. 4, 1978, pp. 250-251.
Acta Neurol. Scandinav, 50, (1974), pp. 611-618 (Olsson).
Arteriosclerosis And Thrombosis, vol. 12, No. 11, (1992), pp. 1329-1335 (Lee et al).
TiPS, vol. 13, Jul. 1992, pp. 286-291 (Morganti-Kossmann et al).
Arthritis And Rheumatism, vol. 35, No. 3, Mar. 1992, pp. 351-355 (Aloe et al).
Arthritis And Rheumatism, vol. 27, No. 8, Aug. 1984, pp. 841-844 (Wasserman).
The Journal Of Immunology, vol. 135, No. 2, Aug. 1985, pp. 843s-847s (Levine et al).
The Journal Of Immunology, vol. 142, No. 3, Feb. 1989, pp. 927-931 (Matsuda et al).
British Journal Of Dermatology (1989), 121, pp. 681-688 (Giannetti et al).
Arch Dermatol Res, 277 (1985), pp. 352-358 (Schubert et al).
Eye Science, vol. 2, No. 4 (1986), pp. 245-248 (Mochizuki).
Annals New York Academy Of Sciences, vol. 664 (1992), pp. 425-442 (Sharkey).
Chem Abst 88 (13):83492 1977.
Allerg. Immunol., vol. 19, No. 2-4, 1973, pp. 380-387, V. Astrauskas et al, "Die Wirkung von Antiphologistischen und immunosuppressiven . . . " *Abstract*, p. 383, (English Abstract).
J. Allergy Clin. Immunol., vol. 86, No. 4(2), 1990, pp. 677-683, Mican et al, "Arthritis and mast cell activation", *Abstract*, p. 679, right col., para. 4.
Laboratory Investigation, vol. 48, No. 3, 1983, pp. 332-338, Powell et al, "Early changes in experimental allergic neuritis", *Abstract*, p. 332, left col.
Rheum. Dis. Clin. North. AM., vol. 17, No. 2, 1991, pp. 333-342, Gruber, "Immunoglobulin E, mast cells, endogenous antigens, and arthritis", *Abstract*, *Conclusion*, p. 335, para. 3.
AM. Rev. Resp. Dis., vol. 135, No. 6(2), 1987, pp. S5-S8, Bienenstock et al, "Mast cell involvement in various inflammatory processes", *Introduction*, *Abstract*; Table 1*.
ACTA Neurol. Scand., vol. 81, 1990, pp. 31-36, Kruger PG et al, "Mast cells and multiple sclerosis: a light and electron microscopic study of mast cells in multiple sclerosis emplasizing staining procedures", *Abstract*.
J. AM. Chem. Soc., vol. 79, No. 19, 1957, pp. 5577-5578, Kuehl Jr., et al, "The identification of N-(2-hydroxyethyl)palmitamide as a naturally occurring anti-inflammatory agent", *p. 5577, right col, para. 4*.

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