Inhibition of exoprotein using amine compositions in absorbent a

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert

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424402, 424404, 424434, A61F 1320

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056185545

ABSTRACT:
Absorbent articles, such as catamenial tampons, for absorbing body fluids have included an effective amount of a nitrogen containing compound to substantially inhibit the production of exotoxins by Gram positive bacteria. The compound is one or more nitrogen containing compounds and their salts having the general formula: ##STR1## wherein R.sub.1 is an alkyl group having from about 8 to about 18 carbon atoms; and R.sub.2 and R.sub.3 can be the same or different. R.sub.2 and R.sub.3 are selected from hydrogen and an alkyl group having from 1 to about 18 carbon atoms. The alkyl groups of R.sub.2 and R.sub.3 can have one or more substitutional moieties selected from hydroxyl, carboxyl and carboxyl salts, and imidazoline. A method of inhibiting the production of exoprotein from Gram positive bacteria is also disclosed.

REFERENCES:
patent: 2154449 (1939-04-01), Hoffman et al.
patent: 2190714 (1940-02-01), Hoffman et al.
patent: 2290173 (1940-08-01), Epstein et al.
patent: 2290174 (1940-10-01), Epstein et al.
patent: 2321594 (1943-06-01), Harris
patent: 2340311 (1944-02-01), Donovan
patent: 2440141 (1948-04-01), Donovan
patent: 2466663 (1949-04-01), Russ et al.
patent: 2467884 (1949-04-01), Elias
patent: 2623841 (1952-12-01), Taub
patent: 2854978 (1958-10-01), Millman et al.
patent: 3091241 (1963-05-01), Kellett
patent: 3172817 (1965-03-01), Leupold et al.
patent: 3331742 (1967-07-01), Babayan
patent: 3490454 (1970-01-01), Goldfarb et al.
patent: 3629454 (1971-12-01), Barr et al.
patent: 3639561 (1972-02-01), Gordon et al.
patent: 3652764 (1972-03-01), Lamberti et al.
patent: 3994298 (1976-11-01), Des Marais
patent: 4002775 (1977-01-01), Kabara
patent: 4046914 (1977-09-01), Hallgren et al.
patent: 4067961 (1978-01-01), Laughlin
patent: 4273118 (1981-06-01), Smith
patent: 4286596 (1981-09-01), Rubinstein
patent: 4289824 (1981-09-01), Smith
patent: 4300561 (1981-11-01), Kaczmarzyk et al.
patent: 4343788 (1982-08-01), Mustacich et al.
patent: 4343798 (1982-08-01), Fawzi
patent: 4377167 (1983-03-01), Kaczmarzyk et al.
patent: 4385632 (1983-05-01), Odelhog
patent: 4392848 (1983-07-01), Lucas et al.
patent: 4405323 (1983-09-01), Auerbach
patent: 4406884 (1983-09-01), Fawzi et al.
patent: 4410442 (1983-10-01), Lucas et al.
patent: 4430381 (1984-02-01), Harvey et al.
patent: 4431427 (1984-02-01), Lefren et al.
patent: 4479795 (1984-10-01), Mustacich et al.
patent: 4489097 (1984-12-01), Stone
patent: 4585792 (1986-04-01), Jacob et al.
patent: 4661101 (1987-04-01), Sustmann
patent: 4675014 (1987-06-01), Sustmann et al.
patent: 4722937 (1988-02-01), Jacob et al.
patent: 4752617 (1988-06-01), Kern
patent: 4959341 (1990-09-01), Wallach
patent: 5068064 (1991-11-01), Proietto et al.
patent: 5080902 (1992-01-01), Allenmark et al.
patent: 5201326 (1993-04-01), Kubicki et al.
patent: 5208257 (1993-05-01), Kabara
Article Entitled "A Rapid, Sensitive Method For Detection Of Alkaline Phosphatase-Conjugated Anti-Antibody Of Western Blots" authored by Blake, Johnston, Russell-Jones and Gotschlich Analytical Biochemistry 136, 175-179 (1984).
Aritcle Entitled "Effect of Glycerol Monolaurate on Bacterial Growth and Toxin Production" authored by Schlievert, Deringer, Kim, Projan and Novick, Agents and Chemotherapy, Mar. 1992 (pp. 626-631).
Article "Fatty Acids and Derivatives as Antimicrobial Agents" authored by Kabara (pp. 1-14).
Article "Production of Toxic Shock Syndrome Toxin 1 By Staphylococcus Aureus as Determined by Tampon Disk-Membrane-Agar Method" Authored by Robbins, Reisler, Hehl and Bergdoll, Journal of Clinical Microbiology, Aug. 1987 (pp. 1446-1449).
Aritcle "Toxic Shock Syndrome Staphlococcus Aureaus: Effect of Tampons on Toxic Shock Syndrome Toxin 1 Production" Authored by Schleivert, Blomster and Kelly (pp. 666-671).
Article "Fatty Acids Derivatives as Antimicrobial Agents" Authored by Kabara, Swieczkowski Conley and Truant. Antimicrobial Agents and Chemotherapy, Jul. 1972, pp. 23-28.
Article "Magnesium, Staphylococcus Aureus and Toxic Shock Syndrome" Authored by Kaas Magnesium 1988:7:315-319.
"The Effect of Glycerol Monolaurate on Growth of, and Production of Toxic Shock Syndrome Toxin 1 and Lipase by Staphylococcus Aureus" Authored by Holland, Taylor and Farrell (pp. 41-55).
Article "Toxin and Enzyme Characterization of Staphylococcus Aureus Isolates From Patients With and Without Toxic Shock Syndrome" Authored by Schlievert et al. Annals of Internal Medicine, 1982:96 (Part 2):937-940.
"Detection and Quantitation of Toxic Shock Syndrome Toxin 1 in Vitro and In Vivo by Noncompetitive Enzyme-Linked Immunosorbent Assay" Authored by Rosten et al., Journal of Clinical Microbiology, Feb. 1987: pp. 327-332.
Article "Sequential Vaginal Cultures from Normal Young Women" Authored by Sautter et al. Journal of Clinical Microbiology, May 1980, pp. 479-484.
Article "Emerging Role of Lactobacilli in the Control and Maintenance of the Vaginal Bacterial Microflora" Authored by Redondo-Lopez et al., Reviews of Infectious Diseases--vol. 12, No. 5 pp. 856-872.
Article "Nasal and Vaginal Staphylococcus Aureus in Young Women: Quantitive Studies" Annals of Inernal Medicine, 1982:96 (Part 2):951-953.
Article "Methods for Quantitative and Qualitative Evaluation of Vaginal Microflora during Menstruation" Authored by Onderdonk, Zamarchi, Walsh, Mellor, Munoz and Kass, Applied and Environmental Microbiology, Feb. 1986, pp. 333-339.
Article "The Vaginal Ecosystem", American Journal of Obstetrics and Gynecology, vol. 165, No. 4, Part 2, Oct., 1991.
Article "Vaginal Flora in Health and Disease" Authored by Bryan Larsen, Clinical Obstetrics Gynecology, vol. 36, No. 1, Mar. 1993.
Article "Recovery of Staphylococcus Aureus from Multiple Body Sites in Menstruating Women" Authored by Lansdell et al. Journal of Clinical Microbiology, Sep. 1984 pp. 307-310.
Article "Control of the Microbial Flora of the Vagina by H.sub.2 O.sub.2 -Generating Lactobacilli" Authored By Klebanoff et al., Dept. of Medicine of Obstetrics and Gynecology, The Journal of Infectious Diseases 1991:164:94-100.
Article "Quantitative Bacteriology of the Vaginal Flora" Authored by Bartlett et al., The Journal of Infectious Diseases, vol. 136, No. 2.

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