Stimulation of nerve growth and/or vitality

Details Stimulation of nerve growth and/or vitality Stimulation of nerve growth and/or vitality

1993-11-18

1998-12-01

Grimes, Eric

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514879, 424 851, A61K 3816, A61K 3819

Patent

active

058438920

ABSTRACT:
The protein, cholinergic neuronal differentiation factor (CDF), also known as leukemia inhibitory factor (LIF), is described, together with the use of the polypeptide to stimulate neuron growth and survival in animals either by direct administration or by autotransplantation of adrenal medullary cells converted to the cholinergic phenotype.

REFERENCES:
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Hilton et al., J. Cell. Biochem. 46:21-26 (1991).
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Dunnett et al., Brain Res. 378:357-373 (1986).
Norris, Vertabre Endocrinology, Second Ed., Lea & Febinger, Philadelphia, PA, 1985, pp. 238-249.

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