Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – 25 or more amino acid residues in defined sequence
Patent
1988-06-13
1991-05-21
Moskowitz, Margaret
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
25 or more amino acid residues in defined sequence
530325, 530326, 424 86, 424 89, 514 12, 435 5, C07K 710, C07K 1700
Patent
active
050176870
ABSTRACT:
Four peptides corresponding to regions of the glycoprotein encoded by the env gene of HTLV1 are provided. These peptides which are immunologically reactive with HTLV-1 specific antibodies are useful in assays for detection of HTLV-1 infection or exposure and in compositions to elicit the production of antibodies against HTLV-1 in animals and man.
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Patent Abstract of Japan, vol. 9, No. 145 (C-287) JP 60-28993 published Feb. 14, 1985.
Cianciolo et al., "Inhibition of Lymphocyte Proliferation by a Synthetic Peptide Homologous to Retroviral Envelope Proteins", Science 230:453-455.
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Dialog Accession No. 89-082937/11, "Antigen for Detection of Antibody Against HTLV-1 Used in Peptide Compsn. for Vaccine Against ATL".
Dialog Accession No. 88169913, Parker et al., "Purification of Human Lymphotropic Virus Type I (HTLV-I) by Affinity Chromatography", J. Virol. Met. (1987) 18:243-255.
Dialog Accession no. 86064177, Blomberg et al., "Immunoglobulin G ANtiobodies Binding to a Synthetic Peptide Deduced from the Nucleotide Sequence of the env gene of HTLV-1 in Patients with Leukemia and Rheumatoid Arthritis, HLA Sensitized Persons and Blood Donors", Leuk. Res. (1985) 9:1111-1116.
Dialog Accession No. 84276010, Hattori et al., "Identification of gag and env Gene Products of Human T cell Leukemia Virus (HTLV)", Virol. (1984) 136:338-347.
Horal Peter
Jeansson Stig
Rymo Lars
Svennerholm Bo
Vahlne Anders
Bernstein D.
Moskowitz Margaret
Virovahl, S.A.
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