Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1980-01-14
1981-08-04
Berch, Mark L.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
2602452T, 2603435, 560170, 560171, C07D70508, C07D48704
Patent
active
042821487
ABSTRACT:
Disclosed is a process for the stereocontrolled total synthesis of thienamycin, which synthesis proceeds via intermediate II: ##STR1## wherein R.sup.3 is a readily removable carboxyl protecting group.
REFERENCES:
patent: 4217453 (1980-08-01), Christensen
Liu Thomas M. H.
Melillo David G.
Ryan Kenneth M.
Shinkai Ichiro
Sletzinger Meyer
Arno James A.
Berch Mark L.
Merck & Co. , Inc.
Pfeiffer Hesna J.
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