Memory enhancing and analgesic aminocarbonylcarbamates related t

Details Memory enhancing and analgesic aminocarbonylcarbamates related t Memory enhancing and analgesic aminocarbonylcarbamates related t

1991-08-23

1993-01-05

Berch, Mark L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

548429, C07D48704, A61K 3140

Patent

active

051771012

ABSTRACT:
There are disclosed various derivatives related to physostigmine of the formula below, ##STR1## where Z, R.sub.1 and R.sub.2 are as defined in the specification, which compounds are useful for enhancing cholinergic function, and as analgesic agents.

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patent: 4765985 (1988-08-01), Leeson
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patent: 4900748 (1990-02-01), Brossi
Brossi, specification of SN166824.
Yu, Heterocycles 27, 745 (1988).
Yu, FEBS Letters 234, 127, 130 (1988).
Atack, J. Pharm. Exp. Ther. 249 194-202.
Fritz, Tetrahedron 26, 5821 (1970).

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