Substituted 5-((tetrazolyl)alkenyl)imidazoles and pharmaceutical

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514382, 514340, 548252, 548146, 548215, 548240, 546276, A61K 3141, C07D40112, C07D40314, C07D41314, C07D41414

Patent

active

051770962

ABSTRACT:
Angiotensin II receptor antagonists having the formula: ##STR1## which are useful in regulating hypertension and in the treatment of congestive heart failure, renal failure, and glaucoma, pharmaceutical compositions including these antagonists, and methods of using these compounds to produce angiotensin II receptor antagonism in mammals.

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patent: 4539410 (1985-09-01), Renfroe
patent: 4880804 (1989-11-01), Carini et al.
patent: 4882342 (1989-11-01), von der Saal
Glennon et al., "N-(phtalimidoalkyl) Derivatives of Serotonergic Agents", J. Med. Chem., vol. 32, pp. 1921-1926 (Aug. 1989).
Glennon et al., "Central Serotonin Receptors as Targets for Drug Research", J. Med. Chem., vol. 30, pp. 1-12 (Jan. 1987).

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