Method of inhibiting the surface expression of glycolipid recept

Details Method of inhibiting the surface expression of glycolipid recept Method of inhibiting the surface expression of glycolipid recept

1996-05-20

1998-07-28

Jarvis, William R. A.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

A61K 31445

Patent

active

057863695

ABSTRACT:
A method is disclosed for inhibiting the surface expression of glycolipid receptors for bacteria by subjecting bacteria cells to an inhibitory effective amount of an N-alkyl derivative of 1,5-dideoxy-1,5-imino-D-glucitol in which said alkyl contains from 2-8 carbon atoms.

REFERENCES:
patent: 4065562 (1977-12-01), Ohata et al.
patent: 4182767 (1980-01-01), Murai et al.
patent: 4533668 (1985-08-01), Matsumara et al.
patent: 4639436 (1987-01-01), Junge et al.
patent: 4849430 (1989-07-01), Fleet et al.
patent: 5011829 (1991-04-01), Hirsch et al.
patent: 5030638 (1991-07-01), Partis et al.
Saunier et al., J. Biol. Chem. 257, 14155-14161 (1982).
Elbein, Ann. Rev. Biochem. 56, 497-534 (1987).
NewBrun, Arch. Oral Biol. 28, 531-536 (1982).
Wang et al., Tetrahedron Lett. 34, 403-406 (1993).
Karlsson et al., J. Biol. Chem. 268, 570-576 (1993).
Shukla et al., Biochem. Biophys. Acta 1083, 101-108 (1991).
Shukla and Radin, J. Lipid Res. 32, 713-722 (1991).
Basu, J. Biol. Chem. 248, 1388-1394 (1973).
van Heyningen, Nature 249, 415-417 (1974).
Karlsson, Ann. Rev. Biochem. 58, 309-350 (1989).
Platt et al., Eur. J. Biochem. 208, 187-193 (1992).
Butters and Hughes, In Vitro 17, 831-838 (1981).

Affiliated with

Also associated with

Rating

Method of inhibiting the surface expression of glycolipid recept does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method of inhibiting the surface expression of glycolipid recept, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of inhibiting the surface expression of glycolipid recept will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-23905