Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1990-03-02
1991-05-21
Sutto, Anton H.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514365, 548182, 548183, 548202, A61K 31415, A61K 3138, C07D27720, C07D27732
Patent
active
050175912
ABSTRACT:
This invention relates to novel (aryl or heteroaromatic methyl)-2,2'-1H-biimidazoles; to a process for their production comprising of reacting an appropriate alpha-brominated or alpha-chlorinated, substituted or nonsubstituted, methylated monoaromatic ring compound with 2,2'-bi-1H-imidazole in a solvent such as ethanol in the presence of a base such as sodium hydroxide under reflux conditions; and to pharmaceutical compositions and methods of treating hypertension with such compounds.
REFERENCES:
patent: 4722932 (1988-02-01), Kawasaki et al.
Matthews Donald P.
McCarthy James B.
Whitten Jeffrey P.
Merrell Dow Pharmaceuticals
Richter J.
Stein William J.
Sutto Anton H.
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