Process for the preparation of 3,4-dihydroxybutanoic acid and sa

Details Process for the preparation of 3,4-dihydroxybutanoic acid and sa Process for the preparation of 3,4-dihydroxybutanoic acid and sa

1993-10-27

1994-12-20

Dees, Jose G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acids and salts thereof

562579, 562587, C07C 51285

Patent

active

053747739

ABSTRACT:
A process for the preparation of 3,4-dihydroxybutanoic acid (1) and salts thereof from a glucose source containing 1,4-1inked glucose as a substituent is described. The process uses an alkali metal hdyroxide and hydrogen peroxide to convert the glucose source to (1). The compound (1) is useful as a chemical intermediate to naturally occurring fatty acids and is used to prepare 3,4-dihydroxybutanoic acid-gamma-lactone (2) and furanone (3), particularly stereoisomers of these compounds.

REFERENCES:
patent: 3631189 (1971-12-01), Snapp et al.
Corbett, W. M., et al., J. Chem. Soc. 1431-1435 (1955).
Green, J. W., J. Amer. Chem. Soc. 78:1894-1897 (1956).
Rowell, R. M., et al., Carbohydr. Res. 11:17-25 (1969).
Isbell, H. S., J. Res. Natl. Bur. Stand., 29:227 (1942).
Moody, G. J., Advances in Carbohydr. Chem., 19:149-179 (1964).
Glattfield, J. W. E., et al., J. Amer. Chem. Soc. 40:973-992 (1918).
Nakamura, N., et al., Tetrahedron Letters, 30:2245-2246 (1989).
Zhou, B., et al., J. Amer. Chem. Soc. 105:5925-5926 (1983).
Nakamura, N., et al., Tetrahedron Letters, 31:267-270 (1990).
Isbell, H. S. et al., Carbohydrate Research, 36 C1-C4 (1974).
Isbell, H. S. et al., Carbohydrate Research, 36, 283-291 (1974).
Kirk-Othmer (3rd Edition) vol. 3, p. 944 (1978).

Affiliated with

Also associated with

Rating

Process for the preparation of 3,4-dihydroxybutanoic acid and sa does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Process for the preparation of 3,4-dihydroxybutanoic acid and sa, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Process for the preparation of 3,4-dihydroxybutanoic acid and sa will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2387043