Pyridonecarboxylic acids and their anti-bacterial compositions

Details Pyridonecarboxylic acids and their anti-bacterial compositions Pyridonecarboxylic acids and their anti-bacterial compositions

1989-09-28

1991-05-21

Lee, Mary C.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514312, 546123, 546156, A61K 3147, C07D21554, C07D47104

Patent

active

050175815

ABSTRACT:
A compound of the formula ##STR1## wherein R.sup.1 is hydrogen or a protecting group; R.sup.2 is C.sub.1 -C.sub.3 alkyl or C.sub.3 -C.sub.7 cycloalkyl; R.sup.3 is hydrogen, hydroxy, or amino; R.sup.4 is halogen; R.sup.5 and R.sup.6 each is identically or differently hydrogen or C.sub.1 -C.sub.3 alkyl; W is C.sub.1 -C.sub.3 alkylidene; X is N or C-Y; Y is hydrogen or halogen; or a pharmaceutically acceptable salt thereof, having a more potent antibacterial activity against G(+) and G(-) bacteria than known analogues, useful as antibacterial agents.

REFERENCES:
patent: 4786649 (1988-11-01), Ueda et al.

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