Process for converting loracarbef dihydrate to loracarbef monohy

Details Process for converting loracarbef dihydrate to loracarbef monohy Process for converting loracarbef dihydrate to loracarbef monohy

1993-06-04

1994-12-20

Rizzo, Nicholas

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D48704

Patent

active

053747194

ABSTRACT:
A process for the preparation of the crystalline monohydrate form of the compound of formula (I) ##STR1## which includes exposing the crystalline dihydrate form of the compound of formula (I) to a temperature of between about 50.degree. and 65.degree. C. and a relative humidity of between about 60 to about 100%.

REFERENCES:
patent: 3502663 (1970-03-01), Barnes
patent: 3531481 (1970-09-01), Pfeiffer
patent: 4977257 (1990-12-01), Eckrich et al.

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