Pyridyl-1,2,5-oxadiazolecarboxamide-2-oxides

Details Pyridyl-1,2,5-oxadiazolecarboxamide-2-oxides Pyridyl-1,2,5-oxadiazolecarboxamide-2-oxides

1993-05-25

1994-12-20

Fan, Jane T.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546277, A61K 3144, C07D41304

Patent

active

053746406

ABSTRACT:
The present invention relates to pyridyl-1,2,5-oxadiazolcarboxamide-2-oxides of the general formula I ##STR1## in which one of the radicals R.sup.1 and R.sup.2 represents pyridyl and the other represents ##STR2## and R.sup.3 and R.sup.4 are defined as indicated in claim 1, processes for their preparation and their use.

REFERENCES:
patent: 4356178 (1982-10-01), Schonafinger et al.
patent: 4416893 (1983-11-01), Schonafinger et al.
CA 118 (25): 254819j Ivanuv et al. 1992.
Liebigs Ann. Chem., 1990, pp. 335-338.
Ann. Chim. (Rome) 1968, vol. 58, pp. 200-212.
"Nitric Oxide" by Burnett et al., Science, Vo. 257, (1992), pp. 401, 403.
"Biological Roles of Nitric Oxide" by Snyder et al., Medicine Scientific American, May 1992, pp. 22-29.
Chemical Abstract, vol. 105 (1986), Abstract No. 114403a.

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