Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Ester doai
Patent
1988-12-16
1991-11-26
Shah, Mukund J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Ester doai
514575, 560314, 562623, C07C27568, A61K 3117
Patent
active
050682512
ABSTRACT:
Compounds of the formula: ##STR1## wherein A is CH.sub.2 ; n is 0 or 1; R.sub.1 and R.sub.2 are independently selected from the group consisting of hydrogen, alkyl, alkenyl, aralkyl and cycloalkyl; Z is the residue from a non-steroidal anti-inflammatory carboxylic acid compound; and M is a pharmaceutically acceptable cation or a metabolically cleavable group; and the pharmaceutically acceptable salts thereof; and a non toxic pharmaceutically acceptable carrier.
These compounds are useful as inhibitors of 5-lipoxygenase.
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Brooks Dee W.
Rodriques Karen E.
Abbott Laboratories
Janssen Jerry F.
Shah Mukund J.
Ward E. C.
Weinstock Steven F.
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