Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Bacteria or actinomycetales; media therefor
Patent
1990-08-13
1994-12-20
Wax, Robert A.
Chemistry: molecular biology and microbiology
Micro-organism, per se ; compositions thereof; proces of...
Bacteria or actinomycetales; media therefor
435194, 43525233, 4353201, 536 232, C12N 912, C12N 1500, C12N 120
Patent
active
053745531
ABSTRACT:
A purified thermostable enzyme is derived from the eubacterium Thermotoga maritima. The enzyme has a molecular weight of about 97 kilodaltons and DNA polymerase I activity. The enzyme can be produced from native or recombinant host cells and can be used with primers and nucleoside triphosphates in a temperaturecycling chain reaction where at least one nucleic acid sequence is amplified in quantity from an existing sequence.
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Gelfand David H.
Lawyer Frances C.
Gould George M.
Hendricks Keith D.
Hoffmann-La Roche Inc.
Sias Stacey R.
Tramaloni Dennis P.
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