Amino acid sequence for a functional human interleukin-8 recepto

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues

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C07K 1300

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053745060

ABSTRACT:
A cDNA clone from HL60 neutrophils, designated p2, which encodes a human interleukin-8 receptor. This IL-8 receptor can be expressed in oocytes or transfected host cells. This receptor has 77% amino acid identity with a second human neutrophil receptor isotype that also binds IL-8. It also exhibits 69% amino acid identity with a protein reported to be an N-formyl peptide receptor from rabbit neutrophils.

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