Methods for preventing headaches

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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514212, 514422, A61K 3140, A61K 31445, A61K 3155

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active

060082321

ABSTRACT:
A method of preventing headache in a human is disclosed which comprises the administration to a human in need thereof of an effective amount of a compound of formula I ##STR1## wherein R.sup.1 and R.sup.3 are, independently, --H, --CH.sub.3, --CO(C.sub.1 -C.sub.6 alkyl), or --COAr, where Ar is optionally substituted phenyl;
R.sup.2 is selected from the group consisting of pyrrolidine, piperidine, and hexamethyleneimino; or
a pharmaceutically acceptable salt or solvate thereof.

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