Proteases, compositions capable of binding to said site, and met

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Hydrolase

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

435212, 435213, 536 232, C12N 950

Patent

active

060080337

ABSTRACT:
Novel herpes viral protease crystalline structures are identified which have an active site formed by the three amino acids Ser, His and His. Also disclosed are methods of identifying inhibitors of these proteases and/or active sites.

REFERENCES:
patent: 4886646 (1989-12-01), Carter et al.
patent: 5434074 (1995-07-01), Gibson et al.
patent: 5478727 (1995-12-01), Roizman et al.
patent: 5486470 (1996-01-01), Darke et al.
patent: 5849296 (1998-12-01), Navia et al.
Steffy et al. "Nucleotide sequence of the herpes simplex virus type 2 gene encoding the protease and capsid protein ICP35" J. Gen. Virol. 76, 1069-1072, 1995.
Davison et al. "The complete DNA sequence of varicella-zoster virus" J. Gen. Virol. 67, 1759-1816, 1986.
Schmidt, et al. J. Biol. Chem. 272: pp. 7732-7735 (1997).
Qui, et al. Nature 383: pp. 275-279 (1996).
Tong, et al. Nature 383: pp. 272-275 (1996).
Qui, et al. Proc. Natl. Acad. Sci. USA 94: pp. 2874-2879 (1997).
Chen, et al. Cell 66: pp. 835-843 (1996).
Shieh, et al. Nature 383: pp. 279-282(1996).
Hoog, et al. Biochemistry 36: pp. 14023-14029 (1997).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Proteases, compositions capable of binding to said site, and met does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Proteases, compositions capable of binding to said site, and met, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Proteases, compositions capable of binding to said site, and met will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-2381552

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.