Nucleic acid probes and methods for detecting pathogenic candida

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid

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935 911, 935270, 935921, 935922, 935923, 935924, 536 2432, 536 2433, 536 253, 435 77, 435 78, C12Q 168, C12P 1934, C12N 100, C07H 1700

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054037107

ABSTRACT:
Nucleic acid probes are described for detecting yeasts capable of causing Candida infection, specifically yeasts of the genera Candida, Torulopsis, and Yarrowia. The preferred probes are complementary to ribonucleic acid sequences unique to specific Candida species, or groups of such species, and as such can detect the rRNA, rDNA, or polymerase chain reaction amplification products of these genes. Methods for detecting the etiological agent of human Candida fungemia utilizing these probes are also provided.

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