Nucleic acid probes and methods for detecting fungi

Details Nucleic acid probes and methods for detecting fungi Nucleic acid probes and methods for detecting fungi

1991-10-22

1994-06-28

Parr, Margaret

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

536 243, 536 2432, 536 2433, C12C 168, C07H 2104

Patent

active

053246322

ABSTRACT:
Nucleic acid probes are described for detecting fungi capable of causing fungal septicemia or capable of causing food spoilage. The preferred probes are complementary to ribonucleic acid sequences found in numerous fungi and absent in animal or plant genomes. As such, these probes can detect the rRNA, rDNA, or polymerase chain reaction amplification products from the majority of fungal species. The detection of etiological agents of human fungemia, the clinical diagnosis of this disease and the direct evaluation of food or beverage fungal content utilizing rRNA or rDNA probes is now possible.

REFERENCES:
patent: 4851330 (1989-07-01), Kohne
Nucleic Acid Sequence Printout (Aug. 17, 1992), pp. 1-9.
Matthews et al. Analytical Biochem. 169: 1-25, 1988 (Feb. 1988).
Cooper et al. in "Manual of Clinical Microbiology" ed. Lennette, E. H. pp. 526-541, 1985.

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