Antibiotic A-33853 derivatives

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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424263, C07D41312

Patent

active

044318090

ABSTRACT:
Antibiotic A-33853 is produced by submerged, aerobic fermentation of a new Streptomyces sp. NRRL 12068. The antibiotic and the diacetyl and triacetyl derivatives thereof disclosed herein have shown antibacterial activity against Staphylococcus and Streptococcus species which are penicillin resistant. In addition, the antibiotic and its tetraacetyl derivative have shown antiviral and antitrichomonal activity in vitro.

REFERENCES:
patent: 4306021 (1981-12-01), Dolak et al.
Dolak et al., II, J. Antibiotics 1980, vol. 33(11), pp. 1391-1394.

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