Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1982-03-08
1984-02-14
Ford, John M.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
424274, 544 13, 548452, 548533, C07D28524, A61K 3140, A61K 3154, C07D41712
Patent
active
044316445
ABSTRACT:
Compounds of the formula ##STR1## and the pharmaceutically acceptable salts thereof, wherein R.sup.1, R.sup.2 and R.sup.4 are independently selected from hydrogen and lower alkyl; R.sup.3 is hydrogen, lower alkyl or amino lower alkyl; A and B taken together with the carbons to which they are attached form an alkylene ring having six carbon atoms or A and B are hydrogen; and Z is ##STR2## are disclosed. The compounds are useful as anti-hypertensive agents.
REFERENCES:
patent: 3110716 (1963-11-01), McLamore et al.
Cutting's Handbook of Pharmacology, 6th Ed., Chapter 20, pp. 190-195. (1979).
Doll Ronald J.
Smith Elizabeth M.
Witkowski Joseph T.
Eisen Bruce M.
Ford John M.
Magatti Anita W.
Schering Corporation
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