Cis-4,5-didehydro-13,1 4-didehydro-11-deoxy-17-phenyl-18,19,20-t

Details Cis-4,5-didehydro-13,1 4-didehydro-11-deoxy-17-phenyl-18,19,20-t Cis-4,5-didehydro-13,1 4-didehydro-11-deoxy-17-phenyl-18,19,20-t

1977-08-01

1978-12-19

Killos, Paul J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

562463, C07C17700

Patent

active

041307186

ABSTRACT:
This invention comprises certain analogs of the prostaglandins in which the double bond between C-13 and C-14 is replaced by a triple bond. Also provided in this invention, are novel chemical processes and novel chemical intermediates useful in the preparation of the above prostaglandin analogs. These prostaglandin analogs exhibit prostaglandin-like activity, and are accordingly useful for the same pharmacological purposes as the prostaglandins. Among these purposes are blood pressure lowering, labor induction at term, reproductive-cycle regulation, gastric antisecretory action, and the like.

REFERENCES:
patent: 3984400 (1976-10-01), Eggler

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