Diaminopyrimidines

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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544295, 544313, A61K 31505, C07D40304

Patent

active

045322406

ABSTRACT:
Substituted-phenyl derivatives of 5-(1,4-piperazinyl)-2,4-pyrimidinediamine are effective as antibacterial and antitumor agents. Methods of preparing such compounds, pharmaceutical compositions based thereon, and a method of treating bacterial infections in a mammal in need of such treatment are disclosed.

REFERENCES:
patent: 2562036 (1951-07-01), Halquist et al.
patent: 2748125 (1956-05-01), Hofmann
patent: 3975384 (1976-08-01), Narr et al.
patent: 4166852 (1979-09-01), Loiseau et al.
patent: 4351832 (1982-09-01), Rakhit et al.
Wu et al., "Chemical Abstracts", vol. 84, 1976, Col. 17428c.

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