Use of insulin sensitizing agents to treat hypertension

Details Use of insulin sensitizing agents to treat hypertension Use of insulin sensitizing agents to treat hypertension

1993-04-22

1994-10-18

Cintins, Marianne M.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514365, 514866, A61K 3144, A61K 31425

Patent

active

053569130

ABSTRACT:
The present invention provides a method for treating hypertension in insulin resistant patients comprising the administration of an insulin sensitizing agent, particularly ciglitazone or pioglitazone.

REFERENCES:
patent: 4287200 (1981-09-01), Kawamatsu et al.
patent: 4572912 (1986-02-01), Yoshioka et al.
patent: 4687777 (1987-08-01), Meguro et al.
patent: 5053420 (1991-10-01), Pershadsingh
Chang, A. Y. et al., "Ciglitazone, a New Hypoglycemic Agent: II. Effect on Glucose and Lipid Metabolisms and Insulin Binding in the Adipose Tissue of C57BL/6J-ob/ob and -+/? Mice", Diabetes, vol. 32, No. 9, Sep. 1983, pp. 839-845.
Chang, A. Y. et al., "Ciglitazone, A New Hypoglycemic Agent: I. Studies in ob/ob and db/db Mice, Diabetic Chinese Hamsters, and Normal and Streptozotocin-Diabetic Rats", Diabetes, vol. 32, No. 9, Sep. 1983, pp. 830-838.

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