Fortimicin derivatives and method for production thereof

Details Fortimicin derivatives and method for production thereof Fortimicin derivatives and method for production thereof

1978-04-25

1979-10-02

Brown, Johnnie R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

424180, 424181, 536 4, 536 10, 536 12, C07H 1522

Patent

active

041699424

ABSTRACT:
6'-N-methylfortimicin D and 6'-N-methylfortimicin KE are produced by chemically moidifying fortimicin KE. 6'-N-methylfortimicin D is useful as an antibacterial compound; and 6'-N-methylfortimicin KE is useful as an intermediate in the synthesis of the former compound.

REFERENCES:
patent: 3350387 (1967-10-01), Vanderhaeghe
patent: 3925353 (1975-12-01), Umezawa et al.
patent: 3931400 (1976-01-01), Nara et al.
patent: 3997524 (1976-12-01), Nagabhushan
patent: 4044123 (1977-08-01), Daniels et al.
patent: 4048430 (1977-09-01), Cooper et al.
patent: 4063015 (1977-12-01), Mallams
patent: 4124756 (1978-11-01), Martin et al.

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