Alkenyl-substituted 9-deoxy-6,9-.alpha.-epoxymethano-PG analogs

Details Alkenyl-substituted 9-deoxy-6,9-.alpha.-epoxymethano-PG analogs Alkenyl-substituted 9-deoxy-6,9-.alpha.-epoxymethano-PG analogs

1978-09-11

1979-10-02

Chan, Nicky

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07D31102

Patent

active

041698410

ABSTRACT:
Processes for preparing prostacyclin analogs which are 9-deoxy-6,9-epoxymethano derivatives of prostaglandin F.sub.1.alpha. -type compounds, illustrated, for example, by a compound of the formula ##STR1## wherein .about. indicates alpha or beta configuration; including the products and intermediates produced therein, said products having pharmacological utility.

REFERENCES:
patent: 4123441 (1978-10-01), Johnson
Pace-Asciak et al., Biochem., 10, 3657 (1971).
Pace-Asciak et al., JACS, 98, 2348 (1976).

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