Dual inhibitors of NO synthase and cyclooxygenase, therapeutical

Details Dual inhibitors of NO synthase and cyclooxygenase, therapeutical Dual inhibitors of NO synthase and cyclooxygenase, therapeutical

1992-12-23

1996-01-02

Springer, David B.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

560169, 562440, 5483241, C07D20928, C07D20733, C07C22926, C07C 251/04, A61K 31405, A61K 31155

Patent

active

054809991

ABSTRACT:
The invention relates to compounds of the general formula AB, which may be a salt or an amide, wherein:
A represents a cyclooxygenase inhibitor having an accessible acidic function and
B represents the L-form of arginine analogues of the formula ##STR1## wherein R.sub.1, R.sub.2 and R.sub.3 represent various substituents, process for the preparation of such compounds and pharmaceutical composition thereof.

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