Continuous rotating electrophoresis column and process of using

Chemistry: electrical and wave energy – Processes and products – Electrostatic field or electrical discharge

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204299R, G01N 2726

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active

046421696

ABSTRACT:
A continuous rotating annular electrophoresis column for the separation of chemical mixtures. The principle of separation is similar to the conventional electrophoresis; however, it is different in that the electric field is applied in the axial direction and the column is rotated. By rotating the column, the product path appears as helical bands, each with a characteristic, stationary exit point at some angular coordinate at the bottom of the column. By applying the electric field axially, the bed thickness can be kept thin for effective heat transfer and temperature control. The apparatus can be used in the separations of biochemically active compounds, or to separate, based on the principal of charge, any chemical mixture. The column can also be packed with chromographic materials and thus operate as a electrochromographic separator.

REFERENCES:
patent: 2992979 (1961-07-01), Magnuson et al.
patent: 3556967 (1971-01-01), Anderson
patent: 3616453 (1971-11-01), Phillpet
patent: 3704217 (1972-11-01), Nerenberg
patent: 3814678 (1974-06-01), Fletcher
patent: 3844926 (1974-10-01), Smyth et al.
patent: 4018662 (1977-04-01), Ruhenstroth-Bauer et al.
patent: 4040940 (1977-08-01), Bier
patent: 4141809 (1979-02-01), Aitchison et al.
patent: 4182678 (1980-01-01), Ito
patent: 4315812 (1982-02-01), Karlson
patent: 4358358 (1982-11-01), Rhodes
patent: 4375401 (1983-03-01), Catsimpoolas
patent: 4432849 (1984-02-01), Saito
patent: 4440638 (1984-04-01), Judy et al.
McDonald et al., "Centrifugal Force in Paper Chrometography and Electrophoresis", Analytical Chemistry, vol. 31, No. 5, May '59, pp. 825-829.
Vermeulen, T., et al., "Design Theory and Separations in Preparative-Scale Continuous-Flow Annular-Bed Electrophoresis," Ing. Eng. Chem. Process Des. Develop., 10:91-102 (1971).
Fox, J. B., et al., "Continuous Chromatography Apparatus, Part I, Construction," J. Chromatog., 43:48-54 (1969).
Fox, J. B., "Continuous Chromatography Apparatus, Part II, Operation," J. Chromatog., 43:55-60 (1969).
Nicholas, R. A. and Fox, J. B., "Continuous Chromatography Apparatus, Part III, Application," J. Chromatog., 43:61-65 (1969).
Begovich, J. M., "Multicomponent Separations Using a Continuous Annular Chromatography," Ph.D. Dissertation, University of tennesee, Knoxville, TN (1982).
Begovich, J. M. and Sisson, W. G., "A Rotating Annular Chromatograph for Continuous Separations," submitted to AIChE J.
Chemical Engineering, vol. 90, No. 8, pp. 10-11 (1983).
"Gene-Splicing Methods Move From Lab to Plant", Chemical Engineering, vol. 90, No. 12, p. 25 (1983).

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