Process for the preparation of 2-(thien-2-yl)- and 2-(thien-3-yl

Details Process for the preparation of 2-(thien-2-yl)- and 2-(thien-3-yl Process for the preparation of 2-(thien-2-yl)- and 2-(thien-3-yl

1982-06-29

1984-11-13

Raymond, Richard L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

260944, 546 22, 546114, 549 6, 549 59, 549 60, 549 61, 549 65, 549 68, 549 71, 549 74, 549 75, 564 14, 568 14, C07D33320, C07D40912

Patent

active

044827180

ABSTRACT:
The present invention provides a process for the preparation of 2-(thien-2-yl)- and 2-(thien-3-yl)-ethylamine derivatives of the general formula: ##STR1## in which R.sub.1, in the 2-, 3-, 4- or 5-position, is a hydrogen or halogen atom, a nitro, carboxyl, cyano or amino group, a linear or branched alkyl or alkoxy radical or a heterocyclic or non-heterocyclic aromatic radical, which is optionally mono- or polysubstituted, the aminoethyl chain is in the 2- or 3-position, R.sub.2, R.sub.3 and R.sub.4, which are the same or different, are hydrogen atoms or heterocyclic or non-heterocyclic aromatic radicals, which are optionally mono- or polysubstituted, and Ar is a heterocyclic or non-heterocyclic aromatic radical, which is optionally mono- or polysubstituted.

REFERENCES:
patent: 2983729 (1961-05-01), Meyer et al.
patent: 4075340 (1978-02-01), Maffrand
patent: 4127580 (1978-11-01), Braye
Parcor, Chemical Abstracts, vol. 90 (1979) 72159q.
Parcor, Chemical Abstracts, vol. 91 (1979) 56,977v.

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