Polymeric diffusion matrix containing propranolol

Details Polymeric diffusion matrix containing propranolol Polymeric diffusion matrix containing propranolol

1983-03-28

1984-11-13

Rose, Shep K.

Firearms

424 78, A61L 1503, A61K 970, A61F 1300

Patent

active

044825331

ABSTRACT:
A self-supporting polymeric diffusion matrix provides for the sustained release of propranolol in order to deliver said propranolol to a patient. The matrix comprises from about 1 to about 60% by weight of a polar plasticizer, from about 5 to about 20% by weight polyvinylalcohol having a molecular weight from about 50,000 to about 150,000, from about 10 to about 25% by weight polyvinylalcohol having a molecular weight from about 4,000 to about 15,000, from about 2 to about 30% by weight polyvinylpyrrolidone, and a pharmaceutically effective amount of the propanolol to provide a sustained release of said propranolol over a prolonged period.

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