Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Ester doai
Patent
1987-03-11
1989-07-25
Raymond, Richard L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Ester doai
514824, 514460, 562501, 560119, 560256, 549292, A61K 31195
Patent
active
048514365
ABSTRACT:
Novel 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitors which are useful as antihypercholesterolemic agents and are represented by the following general structural formulae (I) or (II): ##STR1## wherein: n is 1 to 5;
REFERENCES:
patent: 4376863 (1983-03-01), Lam
Alberts, A. W. et al., Proceedings of the National Academy of Sciences, 77, pp. 3957-3961 (Jul. 1980).
Alberts, A. W. American Journal of Cardiology 62, pp. 105-155, (Nov. 1988).
Endo, A., Kuroda, M. and Tanzawa, K FEBS Letters 72, pp. 323-326, (Dec. 1976)
Hoffman William F.
Scolnick Edward
Smith Robert L.
DiPrima Joseph F.
Merck & Co. , Inc.
Owens A. A.
Raymond Richard L.
Winokur Melvin
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