Substituted phenylguanidines and processes for their preparation

Details Substituted phenylguanidines and processes for their preparation Substituted phenylguanidines and processes for their preparation

1976-05-26

1978-05-09

Garner, Vivian

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Recombinant or stably-transformed bacterium encoding one or...

2604025, 2604045, 260465D, 560 25, 560 27, 560 13, 560 9, 560 18, C07C12912

Patent

active

040887804

ABSTRACT:
N-[2-(Substituted amido)phenyl]-N',N"-bis-carbonylguanidines bearing an optionally substituted phenoxy, phenylthio, phenylsulfinyl or phenylsulfonyl group in the 4- or 5-position of the 2-(substituted amido)-phenyl group are anthelmintic agents. The compounds, of which N-(2-acetamido-4-phenylthiophenyl)-N',N"-bis-carbomethoxyguanidine is a typical example, are prepared through the reaction of isothiourea-S-alkyl ether and an appropriately substituted 2-aminoanilide.

REFERENCES:
patent: 3812173 (1974-05-01), Giraudon
patent: 3869503 (1975-03-01), Widdig et al.

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