Method and composition for the detection and diagnosis of Legion

Details Method and composition for the detection and diagnosis of Legion Method and composition for the detection and diagnosis of Legion

1984-02-24

1989-07-25

Warden, Robert J.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

4351722, 435188, 43524027, 435948, 436518, 436519, 436526, 436533, 436534, 436548, 436825, 530350, 530387, 530391, 530806, 530808, 530825, 935104, 935110, A61K 3940, C12N 500, G01N 33569, G01N 33577

Patent

active

048513334

ABSTRACT:
Method and compositions including monoclonal antibodies to a serogroup-common antigen are provided for the detection and diagnosis of Legionella pneumophila. The monoclonal antibodies recognize a proteinaceous antigen of molecular weight 28,000-29,000 Daltons which is detected in at least serogroups 1 through 8 of Legionella pneumophila and is not detected in other common respiratory pathogens.

REFERENCES:
L. H. Gosting et al, Journal of Clinical Microbiology, 20, 1031-1035, 1984.
R. C. Nowinski, Science, 219, 637-644, 1983.
R. M. McKinney et al, Journ. Clin. Microbiol., 12, 395-401, 1980.
W. Ehret et al, Zbl. Bakt. Hyg., I Abt. Orig. A, 255, 33-38, 1983.
M. F. Para et al, Journ. Clin. Microbiol., 18, 895-900, 1983.
J. R. Joly et al, Infect & Immunity, 35, 721-729, 1982.
K. H. Wong et al, Ann. Int. Med., 90, 634-638, 1979.

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