Treatment of insulin-resistant diabetes

Details Treatment of insulin-resistant diabetes Treatment of insulin-resistant diabetes

1995-03-27

1997-10-07

Tsang, Cecilia J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 21, A61K 3736, A61K 3726

Patent

active

056748450

ABSTRACT:
Insulin-like growth factor (IGF) is used for treatment of type A insulin-resistant diabetes by reduction of glucose levels. The treatment is applicable to Mendenhall's Syndrome, Werner Syndrome, leprechaunism, lipoatrophic diabetes, and other lipoatrophies.

REFERENCES:
Diabetic, Journal of the British Association, Supplement of vol. 5, p. 7, 1988, J. D. Quin, et al., "A25. Mendenhall's Syndrome--A Therapeutic Dilemma".
The New England Journal of Medicine, vol. 317, No. 3, pp. 137-140, Jul. 16, 1987, Hans-Peter Guler, M.D., et al., "Short-Term Metabolic Effects of Recombinant Human Insulin-Like Growth Factor in Healthy Adults".
Diabetes/Metabolism Reviews, vol. 1, Nos. 1 & 2, pp. 189-191, 1985, S. I. Taylor, "Receptor Defects in Patients with Extreme Insulin Resistance".
The New England Journal of Medicine, vol. 317, No. 3, 16 Jul. 1987, H.P. Guler et al.: "Short-term metablic effects of recombinant human insulin-like growth factor I in healthy adults", pp. 137-140.
Diabetologia, vol. 31, 1988, Diabetologia Springer-Verlag, Pub., N. Livingston et al.: "Characterisation of insulin-like growth factor 1 receptor in skeletal muscles of normal and insulin resistant subjects", pp. 871-877.

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