Shellac dispersions and coatings, and method of forming aqueous-

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Tablets – lozenges – or pills

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424475, 424480, 424489, 530201, A61K 928

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active

055674380

ABSTRACT:
A method of forming the aqueous-based shellac dispersion includes dissolving a shellac solution in a basic aqueous solvent to form a shellac solution and subsequently combining the shellac solution with an acidic aqueous solution, whereby the shellac precipitates to form the aqueous-based shellac dispersion. A film can be formed by applying the shellac dispersion to a suitable surface and exposing the dispersion to conditions which cause a substantial portion of the shellac particles in the dispersion to fuse, thereby forming a shellac film on the surface. The shellac film does not include any organic solvent for the shellac or any amine-containing shellac salt. A plasticizer can be employed to form a continuous shellac coating on a substrate at significantly reduced temperatures.

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Hagenmaier, R. D., and Shaw, P. E., "Permeability of Shellac Coatings to Gases and Water Vapor," J. Agricultural and Food Chemistry., 39(5):825-829 (1991).
Banker, G. S., and Peck, G. E., "The new, water-based colloidal dispersions," Pharmaceutical Technology, pp. 55-60 (1981, Apr.).
Chang, R. K., et al., "Preparation and evaluation of shellac pseudolatex as an aqueous enteric coating system for pellets," Int'l J. of Pharmaceutics, 60:171-173 (1990).

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