Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...
Patent
1974-09-30
1976-01-06
Drezin, Norman A.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Recombinant or stably-transformed bacterium encoding one or...
424312, 424317, 424318, A61K 3122
Patent
active
039314103
ABSTRACT:
Pharmaceutical preparations in dosage forms and animal feeds (baits) consisting essentially of pharmaceutically acceptable carriers, oral and injectable, compounded with a sublethal, yet effective, amount of a compound having the formula: ##EQU1## wherein R' is a member selected from the group consisting of hydrogen and alkyl of from one to eight carbon atoms, inclusive and R is a member selected from the group consisting of hydrogen and an acyl radical of a hydrocarbon carboxylic acid of one to 18 carbon atoms, inclusive, for inducing sterility in male mammals. Methods for preventing impregnation of females by male mammals which comprises administering systemically to male mammals a sterilizing amount of a compound of the Formula I.
REFERENCES:
patent: 3259649 (1966-07-01), McClure
McClure, Chemical Abstracts 68: 21749(v) 1968.
Borkovec, Insect Chemosterilants (1966) pp. 2, 3, 61-63.
Kimura, Chemical Abstracts 72: 12145a (1970), referring to Japanese Patent 6926463 (11/6/69)
Binon et al., Chemical Abstracts 59: 6248h (1963).
Vessiere, Chemical Abstracts 59: 13810c (1963).
Drezin Norman A.
Killinger John J.
Saliwanchik Roman
The Upjohn Company
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